Welcome!
ALERT Event: Nanoscopy Imaging Using STED 3X Technology – Achieving Resolutions Down to 30nm (Registry Required)
Date: Friday, Nov. 22nd. Time: 11:00 AM – 12:00 PM
Location: Biomedical Research Building, Room 105
Overview:
The seminar will cover the fundamentals and capabilities of STED 3X Nanoscopy and Confocal Super-Resolution technology. STED (Stimulated Emission Depletion) allows for super-resolution imaging purely through optical means, built on a confocal platform. Using the Leica TCS SP8 system, you can achieve 30nm XY and 130nm Z resolutions in STED mode, as well as 140nm XY and 300nm Z resolutions in confocal super-resolution mode, all powered by Leica’s exclusive White Light Laser (tunable from 470–670 nm) in a single system.
Hands-On Training (Registry Required):
Following the seminar, we'll be hosting four one-hour training sessions for STED users from 1:00 PM to 5:00 PM. Due to time constraints, each session will be limited, but it's a fantastic opportunity for our local imaging community.
Please register here. We look forward to seeing you there!
(hide this warning on this page)The CWRU Proteomics and Small Molecule Mass Spectrometry Corein collaboration with the Case Center for Proteomics and Bioinformatics (CPB) was established in 2006. The Core provides state-of-the-art proteomic instrumentation, computational resources and software for systems biology, proteomic methods development, consultation, and training. The proteomics core is highly experienced in both structural and quantitative proteomics and core staff actively collaborates in grant proposals and development of novel technologies that applies proteomics/mass spectrometry to biomedical research. Areas of expertise include the development novel LCMSMS assays, unbiased shotgun quantitative proteomic analyses (label free protein expression and ITRAQ), global phosphoproteomics, post-translation modification analysis, X-ray footprinting MS, and general mass spectrometry services.
| Contact | Phone | ||
| Structural mass spectrometry (partial proteolysis and disulfide identification) | Janna Kiselar | Janna.Kiselar@case.edu | 216-368-0979 |
| Radiolytic Footprinting | |||
| Quantitative Global Phospho Label Free | Daniella Schlatzer | Daniela.schlatzer@case.edu | 216-368-4014 |
| Label Free Protein Expression (iTRAQ and Label Free Quantification) | |||
| Small Molecule Absolute Quantification | |||
| Katy Lundberg | Kathleen.lundberg@case.edu | 216-368-4159 | |
| Posttranslational Modifications (phosphorylation, acetylation, glycosylation, nitrosylation and acetylation) | |||
| General Protein Identification and Intact Protein Analysis | |||
| Affinity Purification Mass Spectrometry (APMS) | |||
| UPLC/HPLC Analytical Services |
Thermo Orbitrap Eclipse Mass Spectrometer
Thermo Orbitrap Exploris 480 Mass Spectrometer
Thermo Orbitrap Q-Exactive Mass Spectrometer
Thermo TSQ Quantum Ultra
Thermo TSQ Quantiva
Thermo TSQ Altis
| Hours | Location |
|
Monday - Friday 8 am - 5 pm |
2109 Adelbert Avenue, BRB 947 Cleveland, Ohio 44106 |
| Name | Role | Phone | Location | |
|---|---|---|---|---|
| Daniela Schlatzer |
Core Director
|
216-368-4014
|
daniela.schlatzer@case.edu
|
BRB 947
|
| Katy Lundberg |
Core Manager
|
kathleen.lundberg@case.edu
|
||
| Xiaolin Li |
Staff-Research Associate
|
xiaolin.li@case.edu
|
||
| Sausan Azzam |
Staff-Research Associate
|
sausan.azzam@case.edu
|
