CWRU Proteomics Core in collaboration with the Case Center for Proteomics and Bioinformatics (CPB) was established in 2006. The Core provides state-of-the-art proteomic instrumentation, computational resources and software for systems biology, proteomic methods development, consultation, and training. The proteomics core is highly experienced in both structural and quantitative proteomics and core staff actively collaborates in grant proposals and development of novel technologies that applies proteomics/mass spectrometry to biomedical research. Areas of expertise include the development novel LCMSMS assays, unbiased shotgun quantitative proteomic analyses (label free protein expression and ITRAQ), global phosphoproteomics, post-translation modification analysis, X-ray footprinting MS, and general mass spectrometry services.
| Contact | Phone | ||
| Structural mass spectrometry (partial proteolysis and disulfide identification) | Janna Kiselar | Janna.kiselar@case.edu | 216-368-0979 |
| Radiolytic Footprinting | |||
| Quantitative Global Phospho Label Free | Daniella Schlatzer | Daniela.schlatzer@case.edu | 216-368-4014 |
| Label Free Protein Expression (iTRAQ and Label Free Quantification) | |||
| Small Molecule Absolute Quantification | |||
| Katy Lundberg | Kathleen.lundberg@case.edu | 216-368-4159 | |
| Posttranslational Modifications (phosphorylation, acetylation, glycosylation, nitrosylation and acetylation) | |||
| General Protein Identification and Intact Protein Analysis | |||
| Affinity Purification Mass Spectrometry (APMS) | |||
| UPLC/HPLC Analytical Services |
Thermo Orbitrap Elite Hybrid Mass Spectrometers
Thermo Orbitrap Velos Pro Mass Spectrometer
Thermo TSQ Quantum Ultra
Thermo TSQ Quantiva
Agilent 6540 Accurate Mass Q-TOF
Mark R. Chance
Director
Janna Kiselar
Assistant Director
Daniella Schlatzer
Proteomics Manager
| Name | Role |
| Daniela Schlatzer | Proteomics Manager |
| Katy Lundberg | Lab Manager/ RA |
| Xiaolin Li | RA |
| Benliang Wang | SRA |
| Sausan Azzam | SRA |
| Liwen Wang | SRA |
| Fred Hazlett | RA IV |
| Hours | Location |
|
Monday - Friday 8 am - 5 pm |
2109 Adelbert Avenue, BRB 947 Cleveland, Ohio 44106 |
| Name | Role | Phone | Location | |
|---|---|---|---|---|
| Daniela Schlatzer |
Proteomics Manager
|
216-368-4014
|
dms73@case.edu
|
BRB 947
|
