About

Proteomics and Small Molecule Mass Spectrometry Core

Overview of Services

The CWRU Proteomics and Small Molecule Mass Spectrometry Corein collaboration with the Case Center for Proteomics and Bioinformatics (CPB) was established in 2006. The Core provides state-of-the-art proteomic instrumentation, computational resources and software for systems biology, proteomic methods development, consultation, and training. The proteomics core is highly experienced in both structural and quantitative proteomics and core staff actively collaborates in grant proposals and development of novel technologies that applies proteomics/mass spectrometry to biomedical research.   Areas of expertise include the development novel LCMSMS assays, unbiased shotgun quantitative proteomic analyses (label free protein expression and ITRAQ), global phosphoproteomics, post-translation modification analysis, X-ray footprinting MS, and general mass spectrometry services.

Services

  Contact Email Phone
Structural mass spectrometry (partial proteolysis and disulfide identification) Janna Kiselar Janna.Kiselar@case.edu 216-368-0979
Radiolytic Footprinting      
       
       
Quantitative Global Phospho Label Free Daniella Schlatzer Daniela.schlatzer@case.edu 216-368-4014
Label Free Protein Expression (iTRAQ and Label Free Quantification)      
Small Molecule Absolute Quantification      
       
  Katy Lundberg Kathleen.lundberg@case.edu 216-368-4159
Posttranslational Modifications (phosphorylation, acetylation, glycosylation, nitrosylation and acetylation)      
General Protein Identification and Intact Protein Analysis      
Affinity Purification Mass Spectrometry (APMS)      
UPLC/HPLC Analytical Services      

 

Equipment

Thermo Orbitrap Eclipse Mass Spectrometer

Thermo OrbitrapElite Hybrid Mass Spectrometer

Thermo TSQ Quantum Ultra

Thermo TSQ Quantiva

Thermo TSQ Altis

 

 

Leadership

Daniella Schlatzer

Proteomics Manager

 

Staff

Name Role
Daniela Schlatzer Proteomics Manager
Katy Lundberg Lab Manager/ RA
Xiaolin Li SRA
Benliang Wang SRA
Sausan Azzam SRA
Fred Hazlett RA IV
   

Location and hours of operation

Hours Location

Monday - Friday    

8 am - 5 pm 

2109 Adelbert Avenue, BRB 947

Cleveland, Ohio 44106

Links and Resources

  1. Institution core webpage
  2. School of Medicine webpage

Contacts

Name Role Phone Email Location
Daniela Schlatzer
Proteomics Manager
 
216-368-4014
 
dms73@case.edu
 
BRB 947