ATTENTION ⚠️
In Observance of a U.S. Holiday Agilent Cross Lab/ iLab Operations Software Support Help Desk will be closed during U.S. hours on Thursday July 4th and Friday July 5th, 2024. We will resume regular U.S. support hours on Monday July 8th, 2024. EU and APAC Support will remain open during this time. For urgent matters, please add "Urgent" to the ticket/ email subject or press "1", when prompted, to escalate a call on the iLab Support phone and we will prioritize those requests first.
LightSheet Microscopy Seminar
Join us for an insightful seminar highlighting the latest advancements in LightSheet-based imaging platforms, including Cleared Tissue LightSheet and Lattice LightSheet. These cutting-edge technologies are ideal for imaging single molecules to whole organisms, offering live cell imaging capabilities that surpass the limitations of traditional confocal modalities.
Date: July 16th
Time: 2:00 PM - 3:45 PM
Location: Biomedical Research Building, Room 105
We highly encourage you to register for this exciting event. Please contact somlmic@case.edu for further details.
(hide this warning on this page)The Athymic Animal & Xenograft Core consists of two physical sites, one at Case Western Reserve University and one at Cleveland Clinic at the Taussig Cancer Institute. The purpose of the core is to help principal investigators of CWRU and Cleveland Clinic perform tumor experiments, angiogenesis studies, and pharmacokinetic studies in mice. The Core routinely conducts animal experiments involving several syngeneic murine tumor models, and several human xenograft (athymic nude mouse, and NSG – NOD scid IL2Rg mouse) tumor models. In addition, the Core has developed several orthotopic tumor models: brain, lung, breast, renal, spleen, skin, ovarian, prostate, bladder, and pancreas. The Core is always willing to develop additional new models.
Core services utilize murine models to facilitate in vivo cancer drug screening, drug evaluation and drug development. Core services include drug administration (sub-cutaneous, intravenous, intraperitoneal, prolonged slow-release silastic capsule), blood drawing (repetitive - saphenous vein, or terminal – cardiac puncture) for pharmacokinetic pharmacodynamic (PK/PD) studies, absorption distribution metabolism excretion (ADME) studies, syngeneic and xenograft tumor models, orthotopic tumor models. The goal is to help in evaluation of new pharmacologic agents by providing data on tumor growth, metastasis, angiogenesis, and gene expression. The facility also provides consultation services to assist the investigator in all aspects of animal tumor model development.
Name | Role | Phone | Location | |
Dr. William Schiemann | Director | 216 368 5763 | wps20@case.edu | Wood Building, 4th floor |
Mamuni Swain | Core Manager | 216 368 0453 & 216 368 3972 | mxs1272@case.edu | WG-18 and HSAF Ultrabarrier |
Hours | Location |
Monday - Friday 9 AM - 4 PM |
Health Sciences animal facilities and WG-18 Cleveland, OH 44106 |
Name | Role | Phone | Location | |
---|---|---|---|---|
Mamuni Swain |
Core Manager
|
248-787-8277
|
mxs1272@case.edu
|
WG18
|