Applied Functional Genomics Core




Overview of Services

The Applied Functional Genomics Core (AFGC) offers functional genomic study design and a highly standardized, top-to-bottom platform for conducting RNA isolation, Illumina-based RNA sequencing, and bioinformatics on a wide variety of clinical sample types.

We provide workflows that are optimized for many difficult sample types, such as ultra-low input (biopsies, laser capture, small cell numbers), 10X Genomics single cell-multiomic sequencing (scRNA-/snRNA-/ATAC-Seq), and Spatial Profiling via 10X Genomics' Visium CytAssist and Nanostring's GeoMx/nCounter platforms.

Our analysis tools can integrate multiple data types, whether clinical or functional, in the bioinformatics analysis to uncover biomarkers or correlates. Our advanced bioinformatics methods include pathway, network, meta-analysis and drug discovery for researchers who require a look at biology across different studies, especially in correlation with clinical and immunophenotyping data.

The Applied Functional Genomics Core also serves as an assay and analytics platform for the Case Comprehensive Cancer Center's Integrated Genomics Shared Resource and the Rustbelt CFAR Biostatistics and Systems Biology Core (BSB). The CFAR BSB Core also backs the Inter-CFAR Integrated Analysis Group to support a unique partnership between the Rustbelt CFAR and the University of Miami CFAR, thus providing access to other omic technologies and meta-analysis for external CFAR members, and data integration.



Mark Cameron, Core Director, 216.368.3196,, Wood Building W113C

Cheryl Cameron, Project Director, 440.991.7899,, BRB 9th Floor, Room 936

Banu Tamilselvan, Senior Genomics Research Associate (RNASeq Platforms), 216.233.7958,, RT100-5 Research Tower Wood Building

Leah Zagore, Senior Genomics Research Associate (Spatial Platforms), 216.368.8748,, Wood Building W113A

Brian Richardson, Bioinformatics Manager,  216.368.4662,, WRB-1210

Carmen Nichols, Senior Administrative Associate,  216-368-8748,,  Wood Building 113B


Location/Shipping Address

Case Western Reserve University
2109 Adelbert Rd.
Wood Research Tower, RT100-5
Cleveland OH
Tel: 216-233-7958



Name Role Phone Email Location
Mark Cameron
Core Director
Wood W113B
Cheryl Cameron
Project Director
BRB 936

Service List

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