Welcome!
The Applied Functional Genomics Core (AFGC) offers functional genomic study design and a highly standardized, top-to-bottom platform for conducting RNA isolation, Illumina-based RNA sequencing, and bioinformatics on a wide variety of clinical sample types. We provide workflows that are optimized for many difficult sample types, such as ultra-low input (biopsies, laser capture, small cell numbers) and 10X Genomics single cell-sequencing (scRNA-Seq) and Spatial/Visium RNA sequencing, and our analysis tools can integrate multiple data types, whether clinical or functional, in the bioinformatics analysis to uncover biomarkers or correlates. Our advanced bioinformatics methods include pathway, network, and meta-analysis for researchers who require a look at biology across different studies, especially in correlation with clinical and immunophenotyping data.
The Applied Functional Genomics Core also serves as the assay and analytics platform for the Case Comprehensive Cancer Center's Bioinformatic Core and the Rustbelt CFAR Biostatistics and Systems Biology Core (BSB). The CFAR BSB Core also houses the Inter-CFAR Integrated Analysis Group to support a unique partnership between the Rustbelt CFAR and the University of Miami CFAR, thus providing access to other omic technologies and meta-analysis for external CFAR members, and data integration.
*** Due to campus-wide restrictions during COVID-19, the AFGC is operating at reduced staffing levels. Communications and turn-around times have been impacted ***
Contacts
|
Mark Cameron |
Cheryl Cameron |
Banu Tamilselvan |
Brian Richardson |
Dennis Gruszka |
|
|
Core Director |
Project Director / Immunophenotyping and Sorting |
Core Manager |
Bioinformatics Manager |
Operations & QC/QA Manager |
|
|
216.368.3196 |
440.991.7899 |
216.233.7958 |
216.368.4662 |
216.368.1105 |
|
|
mjc230@case.edu |
cxc724@case.edu |
bxt181@case.edu |
bxr183@case.edu |
drg59@case.edu |
|
|
Wood Building W113B |
BRB 9th Floor, Room 936 |
RT100-5 Research Tower Wood Building |
WRB-1210 |
RT100-5 (W113) Research Tower Wood Building |
|
Hours of Operation and Location
|
9 AM - 5 PM |
RT100-5, Wood Research Tower, RNA Center |
|
|
Shipping address
AFGC
Case Western Reserve University
2123 Adelbert Rd.
Wood Research Tower, RT100-5
Cleveland OH
44106-2624
Tel: 216-368-4662
| Name | Role | Phone | Location | |
|---|---|---|---|---|
| Mark Cameron |
Core Director
|
216.368.3196
|
mjc230
|
Wood W113B
|
| Cheryl Cameron |
Project Director / Immunophenotyping and Sorting
|
440.991.7899
|
cxc724
|
BRB 936
|
| Banu Tamilselvan |
Core Manager
|
216.368.4662
|
bxt181
|
Wood Research Tower RT100-5
|
| Dennis Gruszka |
Operations & QC/QA Manager
|
216.368.1105
|
drg59
|
Wood W113
|
