Applied Functional Genomics Core


Overview of Services

The Applied Functional Genomics Core (AFGC) offers functional genomic study design and a highly standardized, top-to-bottom platform for conducting RNA isolation, Illumina-based RNA sequencing, and bioinformatics on a wide variety of clinical sample types. We provide workflows that are optimized for many difficult sample types, such as ultra-low input (biopsies, laser capture, small cell numbers) and 10X Genomics single cell-sequencing (scRNA-Seq), and our analysis tools can integrate multiple data types, whether clinical or functional, in the bioinformatics analysis to uncover biomarkers or correlates. Our advanced bioinformatics methods include pathway, network, and meta-analysis for researchers who require a look at biology across different studies, especially in correlation with clinical and immunophenotyping data.  


The Applied Functional Genomics Core also serves as the assay and analytics platform for the Case Comprehensive Cancer Center's Bioinformatic Core and the Rustbelt CFAR Biostatistics and Systems Biology Core (BSB). The CFAR BSB Core also houses the Inter-CFAR Integrated Analysis Group to support a unique partnership between the Rustbelt CFAR and the University of Miami CFAR, thus providing access to other omic technologies and meta-analysis for external CFAR members, and data integration.


*** Due to campus-wide restrictions during COVID-19, the AFGC is operating at reduced staffing levels.  Communications and turn-around times have been impacted ***  





Mark Cameron

Cheryl Cameron

Banu Tamilselvan

Brian Richardson

 Jackelyn Golden


Core Director

Project Director / Immunophenotyping and Sorting

Core Manager

Bioinformatics Manager

 QC/QA Manager








 BRB 9th Flr Room 936

RT-105 Research Tower Wood Building





Hours of Operation and Location 

9 AM - 5 PM
Monday - Friday

RT-105, Wood Research Tower, RNA Center
Cleveland, OH 44106