Applied Functional Genomics Core

 

Overview of Services

The Applied Functional Genomics Core (AFGC) partners with the CWRU Genomics Core to offer functional genomic study design and a highly standardized, top-to-bottom platform for conducting RNA isolation, Illumina-based RNA sequencing, and advanced bioinformatics on a wide variety of clinical sample types. We provide workflows that are optimized for many difficult sample types, such as ultra-low input (biopsies, small cell numbers), single cell sequencing (10X Genomics Chromium platform), and our analysis tools can integrate multiple data types, whether clinical or functional, in the bioinformatics analysis to uncover biomarkers or correlates. Our advanced bioinformatics methods include pathway and network analysis, meta-analysis, and “Mixomics” for researchers who require a look at biology across very different studies, especially in correlation with immunophenotyping data.

 

The Applied Functional Genomics Core also serves as the assay and analytics platform for the Cleveland CFAR Experimental and Analytic Systems Biology Core (EASB). The EASB Core houses the Inter-CFAR Bioinformatic Network to support a unique partnership between the Cleveland CFAR and the University of Miami CFAR, thus providing access to other omic technologies and meta-analysis for external CFAR members, and data integration.

 

 

 

Team 

 

Mark Cameron

Cheryl Cameron

Michael Cartwright

Brian Richardson

Carmen Nichols

Jackelyn Golden

Core Director

Project Director / Immunophenotyping and Sorting

Core Manager

Bioinformatics Manager

Operations

QC/QA

216.368.3196

216.368.4699

216.368.4662

216.368.4699

216.368.4662

216.368.4699

mjc230@case.edu

cxc724@case.edu

mjc239@case.edu

bxr183@case.edu

 cnn4case@gmail.com

jxg406@case.edu

WRB-1314

WRB-1210

Wood W-G4

WRB-1210

Wood W-G4

WRB-1210

 

Hours of Operation and Location 

8 AM - 4 PM
Monday - Friday

Wood Building, W-G4
Cleveland, OH 44106