Applied Functional Genomics Core

 

Overview of Services

The Applied Functional Genomics Core (AFGC) offers functional genomic study design and a highly standardized, top-to-bottom platform for conducting RNA isolation, Illumina-based RNA sequencing, and bioinformatics on a wide variety of clinical sample types. We provide workflows that are optimized for many difficult sample types, such as ultra-low input (biopsies, laser capture, small cell numbers) and 10X Genomics single cell-sequencing (scRNA-Seq), and our analysis tools can integrate multiple data types, whether clinical or functional, in the bioinformatics analysis to uncover biomarkers or correlates. Our advanced bioinformatics methods include pathway, network, and meta-analysis for researchers who require a look at biology across different studies, especially in correlation with clinical and immunophenotyping data.  

 

The Applied Functional Genomics Core also serves as the assay and analytics platform for the Case Comprehensive Cancer Center's Bioinformatic Core and the Rustbelt CFAR Biostatistics and Systems Biology Core (BSB). The CFAR BSB Core also houses the Inter-CFAR Integrated Analysis Group to support a unique partnership between the Rustbelt CFAR and the University of Miami CFAR, thus providing access to other omic technologies and meta-analysis for external CFAR members, and data integration.

 

*** Due to campus-wide restrictions during COVID-19, the AFGC is operating at reduced staffing levels.  Communications and turn-around times have been impacted ***  

 

 

Team 

 

Mark Cameron

Cheryl Cameron

Banu Tamilselvan

Brian Richardson

 Jackelyn Golden

 

Core Director

Project Director / Immunophenotyping and Sorting

Core Manager

Bioinformatics Manager

 QC/QA Manager

 

216.368.3196

 440.991.7899

 

 

 

 

mjc230@case.edu

cxc724@case.edu

bxt181@case.edu

bxr183@case.edu

 

 

WRB-1314

 BRB 9th Flr Room 936

RT-105 Research Tower Wood Building

 

 

 

 

Hours of Operation and Location 

9 AM - 5 PM
Monday - Friday

RT-105, Wood Research Tower, RNA Center
Cleveland, OH 44106