Welcome!
ALERT ATTENTION ⚠️
In observance of a holiday, Agilent CrossLab/iLab Operations Software Support Help Desk will be closed during U.S. hours on Friday, July 4th, 2025. We will resume regular U.S. support hours on Monday, July 7th, 2025. EU and APAC Support will remain open during this time. For urgent matters, please add "Urgent" to the ticket/email subject or press "1" when prompted to escalate a call on the iLab Support phone, and we will prioritize those requests first.
The Applied Functional Genomics Core (AFGC) offers functional genomic study design and a highly standardized, top-to-bottom platform for conducting RNA isolation, Illumina-based RNA sequencing, and bioinformatics on a wide variety of clinical sample types.
We provide workflows that are optimized for many difficult sample types, such as ultra-low input (biopsies, laser capture, small cell numbers), 10X Genomics single cell-multiomic sequencing (scRNA-/snRNA-/ATAC-Seq), and Spatial Profiling via 10X Genomics' Visium CytAssist and Nanostring's GeoMx/nCounter platforms.
Our analysis tools can integrate multiple data types, whether clinical or functional, in the bioinformatics analysis to uncover biomarkers or correlates. Our advanced bioinformatics methods include pathway, network, meta-analysis and drug discovery for researchers who require a look at biology across different studies, especially in correlation with clinical and immunophenotyping data.
The Applied Functional Genomics Core also serves as an assay and analytics platform for the Case Comprehensive Cancer Center's Integrated Genomics Shared Resource and the Rustbelt CFAR Biostatistics and Systems Biology Core (BSB). The CFAR BSB Core also backs the Inter-CFAR Integrated Analysis Group to support a unique partnership between the Rustbelt CFAR and the University of Miami CFAR, thus providing access to other omic technologies and meta-analysis for external CFAR members, and data integration.
*** Please note we are currently short-staffed due to rapidly changing support levels and increased supplier costs. Please contact the core director(s) directly for engagement and operational updates ***
Location/Shipping Address
AFGC
Case Western Reserve University
2109 Adelbert Rd.
Wood Research Tower, RT100-5
Cleveland OH
44106-2624
Tel: 216-233-7958
| Name | Role | Phone | Location | |
|---|---|---|---|---|
| Mark Cameron |
Director
|
216-368-3196
|
mark.cameron@case.edu
|
Wood Building W113C
|
| Cheryl Cameron |
Co-Director
|
440-991-7899
|
cheryl.cameron@case.edu
|
BRB 936
|
| Banu Tamilselvan |
Staff-Senior Genomics Research Associate (RNASeq Platforms)
|
216-233-7958
|
banumathi.tamilselvan@case.edu
|
RT100-5 Research Tower Wood Building
|
| Leah Zagore |
Staff-Senior Genomics Research Associate (Spatial Platforms)
|
216-368-8748
|
leah.mccord@case.edu
|
W113A
|
| Brian Richardson |
Staff-Senior Bioinformatics Associate
|
216-368-4662
|
brian.richardson2@case.edu
|
WRB-1210
|
| Service List |
| ► Library Prep (2) | |||
| Name | Description | Price | |
|---|---|---|---|
| Single Cell Multiome ATAC + Gene Expression (10X Genomics) |
Includes transcriptome library prep, AND ATAC-Seq library prep. |
Inquire | |
| Custom Single Cell Library Generation Request 10X Genomics |
This option is available for custom requests, i.e. projects with special handling requirements, combined use of multiple platforms, etc. For example if you require the use of a barcoded antibody or custom probes with single cell sequencing. ***Please note that unless otherwise stated, these prices do not include upstream sample processing/isolation or fixation work and price only includes the cost of library generation.*** |
Internal
$1.00
each
External - Academic $1.00 each External - Foundation/Non-profit $1.00 each External - Industry $1.00 each |
|
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