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Applied Functional Genomics Core

Overview of Services

The Applied Functional Genomics Core (AFGC) partners with the CWRU Genomics Core to offer 'omic study design consultation and a highly standardized, top-to-bottom platform for conducting ultra-low input RNA isolation, Illumina-based RNA sequencing, and advanced bioinformatics on a wide variety of clinical sample types. We provide workflows that are optimized for many difficult sample types and our analysis tools can integrate multiple data types, whether clinical or functional, in the bioinformatics analysis to uncover biomarkers or correlates. Our advanced bioinformatics methods include pathway and network analysis, meta-analysis, and “Mixomics” for researchers who require a look at biology across very different studies.

 

The Applied Functional Genomics Core also serves as the transriptomics and bioinformatic platform for the CFAR Experimental and Analytic Systems Biology Core (EASB). We therefore partner with a variety of clinical, CFAR and university cores, for those researchers who require a true top-to-bottom systems biology analysis. The EASB Core also houses the Inter-CFAR Bioinformatic Network to facilitate partnerships between CFARs, providing access to other omic technologies, bioinformatic analysis and meta-analysis for external CFAR members, and data integration between CFARs.

 

Leadership 

Mark Cameron

Pearline Cartwright

Michael Cartwright

Jackelyn Golden

Brian Richardson

Peter Wilkinson

Core Director

Core Manager

Sequencing Manager

QC/QA Manager

Bioinformatician

Sr. Bioinformatician

216.368.2791

216.368.4662

216.368.4662

216.368.4662

216.368.4699

216.368.3371

mjc230@case.edu

pxc336@case.edu

mjc239@case.edu

jxg406@case.edu

bxr183@case.edu

pxw202@case.edu

WRB-1314

WRB-5304

WRB-5304

WRB-1304

WRB-1307

WRB-1308

Hours of Operation and Location 

9 AM - 5 PM
Monday - Friday    

Wolstein Research Building

WRB 5304
2103 Cornell Road
Cleveland, OH 44106