ALERT

Event: Nanoscopy Imaging Using STED 3X Technology – Achieving Resolutions Down to 30nm (Registry Required)
Date: Friday, Nov. 22nd. Time: 11:00 AM – 12:00 PM
Location: Biomedical Research Building, Room 105

Overview:
The seminar will cover the fundamentals and capabilities of STED 3X Nanoscopy and Confocal Super-Resolution technology. STED (Stimulated Emission Depletion) allows for super-resolution imaging purely through optical means, built on a confocal platform. Using the Leica TCS SP8 system, you can achieve 30nm XY and 130nm Z resolutions in STED mode, as well as 140nm XY and 300nm Z resolutions in confocal super-resolution mode, all powered by Leica’s exclusive White Light Laser (tunable from 470–670 nm) in a single system.

Hands-On Training (Registry Required):

Following the seminar, we'll be hosting four one-hour training sessions for STED users from 1:00 PM to 5:00 PM. Due to time constraints, each session will be limited, but it's a fantastic opportunity for our local imaging community.

Please register here. We look forward to seeing you there!

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RNA Profiling Core

Overview of Services

The RNA profiling core provides access to expertise and infrastructure for advanced transcriptomic profiling approaches, including Ribosome Profiling (mapping of translating ribosomes) , CLIP (mapping of RNA-protein binding sites), 3'-end profiling (assessing alternative polyadenylation). The Core assists in designing effective transcriptomic profiling experiments, prepares the sequencing libraries, coordinates the Next Generation Sequencing, provides project–specific data analysis and assists in comprehensive data interpretation and presentation.

Contacts

Name	Role	Phone	Email	Location
Frank A. Tedeschi	Core Manager	368-6711	frank.tedeschi@case.edu	RT100-8
Joseph Luna	Core Director	216-368-3336	joseph.luna@case.edu
RNA Profiling Core	Core Admin		RNAcore@case.edu