CDDRCC Histology

Overview of Services

The Histology Core provides high-quality, cost-effective and time-efficient histological and imaging analysis of human and animal tissues of digestive inflammatory and metabolic diseases, such as inflammatory bowel disease, hepatitis, metabolic syndromes and obesity. These conditions affect millions of individuals in the U.S., and by facilitating their study, we can increase the chance of uncovering key pathogenic mechanisms and developing new therapeutic approaches. 

The core can provide basic, high-quality histologic and immunohistochemistry (IHC) services in a cost-effective and timely fashion. We can also provide initial service, consultation and subsequent training for special IHC staining in gastrointestinal (GI) and liver tissues and provide consistent and validated histological scoring of GI and liver inflammation for preclinical and clinical studies. Furthermore, we can provide publication-ready photo documentation of acquired histological, IHC ­ stained images and provide access to an animal tissue repository of histological blocks and slides of various models of Gl and liver inflammatory and metabolic disease.

Location and hours of operation

Hours Location

 Monday-Friday

 9AM-5PM

Cleveland Digestive Diseases Research Core Center
10900 Euclid Avenue, Cleveland OH 44106-4952

Sample Drop Off

2103 Cornell road

Wolstein Research Building, room 5404

Cleveland 44106

Links and Resources

CDDRCC Histology/Imaging Core

Contacts

Name Role Phone Email Location
Theresa Pizarro
Core Director
 

 
Theresa.pizarro@case.edu
 

 
Carlo De Salvo
Core Manager
 

 
carlo.desalvo@case.edu
 

 
Susan Brill
Core Staff
 

 
susan.brill@case.edu
 

 
Sophie Kochheiser
Core Staff
 

 
sophie.kochheiser@case.edu
 

 

Service list


Search available services:
Name Description Price
Additional tissues/organoids embedding

Additional tissues/organoids embedding per block (each additional tissue/organoid)

Inquire
High quality photomicrographs or whole sllide scannings by Core

High resolution photomicrographs or slides scanning (per hour)

Inquire
Histology Evaluation

Slides scoring for intestinal inflammation, fibrosis, cancer, cell count (slide)

Inquire
IHC/IF (2 day process, established protocol)

IHC/IF staining, established protocol/validated antibodies, up to 20 slides per session, primary antibodies provided by requester (session)

Inquire
IHC/IF (2 day process, establishing new protocol)

Troubleshooting new antibodies for IHC, up to 4 slides, primary antibodies provided by requester (session)

Inquire
Plus + + Slides

Additional cost for special + + slide (slide)

Inquire
Processing/Embedding

Processing and embedding (single tissue or organoid per block)

Inquire
Re-embedding/reorganizing tissues/organoids in new blocks

Re-embedding/reorganizing tissues/organoids (new block)

Inquire
Section Paraffin

Sectioning of paraffin-embedded tissues into slides (slide)

Inquire
Slides box

Slides box, if not provided by requester (100 slides box)

Inquire
Special Stain

Special stain (slide)

Inquire
Staining H&E

H&E staining (slide)

Inquire

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