ALERT

Event: Nanoscopy Imaging Using STED 3X Technology – Achieving Resolutions Down to 30nm (Registry Required)
Date: Friday, Nov. 22nd.   Time: 11:00 AM – 12:00 PM
Location: Biomedical Research Building, Room 105

Overview:
The seminar will cover the fundamentals and capabilities of STED 3X Nanoscopy and Confocal Super-Resolution technology. STED (Stimulated Emission Depletion) allows for super-resolution imaging purely through optical means, built on a confocal platform. Using the Leica TCS SP8 system, you can achieve 30nm XY and 130nm Z resolutions in STED mode, as well as 140nm XY and 300nm Z resolutions in confocal super-resolution mode, all powered by Leica’s exclusive White Light Laser (tunable from 470–670 nm) in a single system.

Hands-On Training (Registry Required):

Following the seminar, we'll be hosting four one-hour training sessions for STED users from 1:00 PM to 5:00 PM. Due to time constraints, each session will be limited, but it's a fantastic opportunity for our local imaging community.

Please register here. We look forward to seeing you there!

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About

Neurodegenerative Research Core

 

Overview

The Neurodegenerative Research Core (NRC) provides Case Western Reserve University (CWRU) investigators and other researchers access to human tissue and bodily fluids collected from patients suspected of prion diseases such as Creutzfeldt-Jakob’s Disease (CJD) and other neurodegenerative diseases. In addition to biorepository services, the NRC offers routine histologic and special stains and immunohistochemical stains specific for neurodegenerative diseases. Lastly, the NRC offers CWRU investigators and other researchers access to essential reagents used to perform Real-Time Quaking-Induced Conversion (RT-QuIC) assays.

Tissue specimens and bodily fluids are available for researchers investigating the following diseases:

  • Creutzfeldt-Jakob Disease (CJD)
  • Variant Creutzfeldt-Jakob Disease (vCJD)
  • Iatrogenic Creutzfeldt-Jakob Disease (iCJD)
  • Gerstmann-Straussler-Scheinker Syndrome (GSS)
  • Fatal Familial Insomnia
  • Genetic CJD (gCJD)
  • Sporadic Fatal Insomnia
  • Variably Protease Sensitive Prionopathy
  • Other neurodegenerative conditions like Alzheimer's disease, dementia with Lewy bodies, frontotemporal lobar degeneration, etc.

Location and hours of operation

Hours Location

Monday-Friday 

9:00 - 4:30 PM

2085 Adelbert Rd Rm 419

Cleveland, Ohio 44106

 Links and Resources

  1. National Prion Disease Pathology Surveillance Center
 

Contacts

Name Role Phone Email Location
Keisi Kotobelli
Data Manager
 
216-368-0587
 
keisi.kotobelli@case.edu
 
Path 419
 
Tatiana Weaver
Laboratory Manager
 
216-368-0587
 
tatiana.weaver@case.edu
 
Path 419
 

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