ALERT

ATTENTION ⚠️

In Observance of U.S. Holiday, Thanksgiving, Agilent Cross Lab/ iLab Operations Software Support Help Desk will be closed during U.S. hours on Thursday November 24th and Friday November 25th, 2022. We will resume regular U.S. support hours on Monday November 28th, 2022. EU and APAC Support will remain open during this time. For urgent matters, please add "Urgent" to the ticket/ email subject or press "1", when prompted, to escalate a call on the iLab Support phone and we will prioritize those requests first.

Neurodegenerative Research Core

 

Overview

The Neurodegenerative Research Core (NRC) provides Case Western Reserve University (CWRU) investigators and other researchers access to human tissue and bodily fluids collected from patients suspected of prion diseases such as Creutzfeldt-Jakob’s Disease (CJD) and other neurodegenerative diseases. In addition to biorepository services, the NRC offers routine histologic and special stains and immunohistochemical stains specific for neurodegenerative diseases. Lastly, the NRC offers CWRU investigators and other researchers access to instrumentation and essential reagents used to perform Real-Time Quaking-Induced Conversion (RT-QuIC) assays.

Tissue specimens and bodily fluids are available for researchers investigating the following diseases:

  • Creutzfeldt-Jakob Disease (CJD)
  • Variant Creutzfeldt-Jakob Disease (vCJD)
  • Iatrogenic Creutzfeldt-Jakob Disease (iCJD)
  • Gerstmann-Straussler-Scheinker Syndrome (GSS)
  • Fatal Familial Insomnia
  • Genetic CJD (gCJD)
  • Sporadic Fatal Insomnia
  • Variably Protease Sensitive Prionopathy
  • Other neurodegenerative conditions like Alzheimer's disease, dementia with Lewy bodies, frontotemporal lobar degeneration, etc.

Location and hours of operation

Hours Location

Monday-Friday 

8:00 - 5:00 PM

2085 Adelbert Rd Rm 419

Cleveland, Ohio 44106

 Staff and Leadership

Name Role Phone Email
Brian Appleby, MD Director 216-368-1274 bsa35@case.edu
Tatiana Weaver Lab Manager 216-368-1447 txw545@case.edu
 Keisi Kotobelli Data Manager 216-368-5722 kxk68@case.edu

Links and Resources

  1. National Prion Disease Pathology Surveillance Center
 

Contacts

Name Role Phone Email Location
Keisi Kotobelli
Data Manager
 
216-368-5722
 
kxk680@case.edu
 
Path 419
 
Tatiana Weaver
Lab Manager
 
216-368-1447
 
txw545@case.edu
 
Path 401
 

Map