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About

Neurodegenerative Research Core

 

Overview

The Neurodegenerative Research Core (NRC) provides Case Western Reserve University (CWRU) investigators and other researchers access to human tissue and bodily fluids collected from patients suspected of prion diseases such as Creutzfeldt-Jakob’s Disease (CJD) and other neurodegenerative diseases. In addition to biorepository services, the NRC offers routine histologic and special stains and immunohistochemical stains specific for neurodegenerative diseases. Lastly, the NRC offers CWRU investigators and other researchers access to essential reagents used to perform Real-Time Quaking-Induced Conversion (RT-QuIC) assays.

Tissue specimens and bodily fluids are available for researchers investigating the following diseases:

  • Creutzfeldt-Jakob Disease (CJD)
  • Variant Creutzfeldt-Jakob Disease (vCJD)
  • Iatrogenic Creutzfeldt-Jakob Disease (iCJD)
  • Gerstmann-Straussler-Scheinker Syndrome (GSS)
  • Fatal Familial Insomnia
  • Genetic CJD (gCJD)
  • Sporadic Fatal Insomnia
  • Variably Protease Sensitive Prionopathy
  • Other neurodegenerative conditions like Alzheimer's disease, dementia with Lewy bodies, frontotemporal lobar degeneration, etc.

Location and hours of operation

Hours Location

Monday-Friday 

9:00 - 4:30 PM

2085 Adelbert Rd Rm 419

Cleveland, Ohio 44106

 Links and Resources

  1. National Prion Disease Pathology Surveillance Center
 

Contacts

Name Role Phone Email Location
Keisi Kotobelli
Data Manager
 
216-368-0587
 
keisi.kotobelli@case.edu
 
Path 419
 
Tatiana Weaver
Laboratory Manager
 
216-368-0587
 
tatiana.weaver@case.edu
 
Path 419
 

Map