Welcome!
ALERT Event: Nanoscopy Imaging Using STED 3X Technology – Achieving Resolutions Down to 30nm (Registry Required)
Date: Friday, Nov. 22nd. Time: 11:00 AM – 12:00 PM
Location: Biomedical Research Building, Room 105
Overview:
The seminar will cover the fundamentals and capabilities of STED 3X Nanoscopy and Confocal Super-Resolution technology. STED (Stimulated Emission Depletion) allows for super-resolution imaging purely through optical means, built on a confocal platform. Using the Leica TCS SP8 system, you can achieve 30nm XY and 130nm Z resolutions in STED mode, as well as 140nm XY and 300nm Z resolutions in confocal super-resolution mode, all powered by Leica’s exclusive White Light Laser (tunable from 470–670 nm) in a single system.
Hands-On Training (Registry Required):
Following the seminar, we'll be hosting four one-hour training sessions for STED users from 1:00 PM to 5:00 PM. Due to time constraints, each session will be limited, but it's a fantastic opportunity for our local imaging community.
Please register here. We look forward to seeing you there!
(hide this warning on this page)
The Mouse Models Core of the Cleveland DDRCC provides members with access to a comprehensive set of services and unique mouse models to support in vivo investigations of digestive diseases involving inflammatory and metabolic processes (i.e., inflammatory bowel disease, hepatitis, obesity and metabolic syndromes). These conditions affect millions of individuals in the U.S., and facilitating their study in mouse models will help uncover key pathogenic mechanisms and develop new therapeutic approaches.
The Cleveland DDRCC Mouse Models Core can provide experimental cohorts of SAMP1/YitFc (SAMP) and TNF∆ARE mice and educate, consult, and train DDRCC investigators in the use of various mouse modeling techniques. The core can also provide high-resolution murine video endoscopy with well-validated scoring of intestinal inflammation and colonic tumors and perform stereomicroscopy on murine intestinal tissues and assess inflammation by 3-D stereomicroscopy with assessment of myeloperoxidase activity.
*** All consultation free for DDRCC members ***
| Hours | Location |
|
Monday - Friday 9 AM - 5 PM |
2109 Adelbert Road |
| Name | Role | Phone | Location | |
|---|---|---|---|---|
| Tracy Krebs, MBA |
Core Manager
|
216-368-6058
|
tracy.krebs@case.edu
|
Biomedical Research Building - Room 523
|
| Fabio Cominelli, MD, PhD |
Co-Director
|
216-844-7344
|
fabio.cominelli@case.edu
|
Biomedical Research Building - Room 524
|
| Alexander Rodriguez-Palacios, DVM, PhD |
Co-Director
|
216-368-8545
|
alexander.rodriguez-palacios@case.edu
|
Biomedical Research Building - Room 525
|
| Service list |
| ► Animal Services (1) | |||
| Name | Description | Price | |
|---|---|---|---|
| Experimental Mouse Cohort |
Breeding and Provision of Experimental Mice (SAMP and TNF∆ARE). Price is per mouse. |
Inquire | |
