Welcome!
The Mouse Models Core of the Cleveland DDRCC provides members with access to a comprehensive set of services and unique mouse models to support in vivo investigations of digestive diseases involving inflammatory and metabolic processes (i.e., inflammatory bowel disease, hepatitis, obesity and metabolic syndromes). These conditions affect millions of individuals in the U.S., and facilitating their study in mouse models will help uncover key pathogenic mechanisms and develop new therapeutic approaches.
The Cleveland DDRCC Mouse Models Core can provide experimental cohorts of SAMP1/YitFc (SAMP) and TNF∆ARE mice and educate, consult, and train DDRCC investigators in the use of various mouse modeling techniques. The core can also provide high-resolution murine video endoscopy with well-validated scoring of intestinal inflammation and colonic tumors and perform stereomicroscopy on murine intestinal tissues and assess inflammation by 3-D stereomicroscopy with assessment of myeloperoxidase activity.
Services:
*** All consultation free for DDRCC members ***
Fabio Cominelli, MD, PhD | Core Director
Alexander Rodriguez-Palalcios, PhD | Manager
Tracy Krebs, MBA | Core Administrator
| Hours | Location |
|
Monday - Friday 8 AM - 4 PM |
2109 Adelbert Road |
| Name | Role | Phone | Location | |
|---|---|---|---|---|
| Tracy Krebs, MBA |
Administrative Manager
|
216-368-6058
|
tls23@case.edu
|
Biomedical Research Building - Room 523
|
| Fabio Cominelli, MD, PhD |
Director
|
216-844-7344
|
fxc90@case.edu
|
Biomedical Research Building - Room 524
|
| Alexander Rodriguez-Palacios, DVM, PhD |
Manager of Mouse Models Core
|
216-368-8545
|
axr503@case.edu
|
Biomedical Research Building - Room 525
|
| Dennis Gruszka |
iLab Support Administrator
|
216-368-1105
|
drg59@case.edu
|
Biomedical Research Building - Room 509
|
