ALERT

2025 Microscopy/Microanalysis Summer School at AMLCI/Kent-State

The Microscopy Summer School 2025 (AMLCI/CCF/MSNO/ACESS) is scheduled for July 24 (online lectures) and 25&28 (lab tours and hands-on demonstrations). Free registration, lecture schedule, and any other information can be found at the Microscopy Society of Northeastern Ohio (MSNO) website: https://www.msneo.org/summerschool2025-amlci.html.

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Xenium In Situ Seminar – Unlock the Power of Single Cell + Spatial Biology

The registration link is provided here: https://docs.google.com/forms/d/e/1FAIpQLSc8c29zNLvlh35dJcotYKTwK5Y_OdT-mPmwy2nnm1Kl88RGsw/viewform

Date: August 11, 2025
Time: 12:00 – 1:00 PM
Location: Wolstein Auditorium (WRB 1413), 2103 Cornell Road, Cleveland, OH 44106
Presenter: Egon Ranghini, PhD | Senior Science & Technology Advisor

Discover how Xenium enables high-plex RNA mapping in FFPE and fresh frozen tissues with subcellular resolution. Join us for an overview of current capabilities, product roadmap insights, and an interactive demo of Xenium Explorer.

Event Promotions:

- Lunch provided

- Event-Only Promotions: 35% off Pilot Projects (limit: 2 slides) - 25% off Standard Projects (no slide limit) Includes Xenium consumables & custom panels | PO required by Sept 15, 2025

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About

Northeast Ohio High Field NMR Facility

Overview of Services

Nuclear Magnetic Resonance (NMR) Spectroscopy is a very versatile technology for the characterization of structure and dynamics of small molecules as well as biological macromolecules in solution (even as part of mixtures and in cells), but also in membrane mimicking environments, in solid powders or microcrystals.  The facility houses state of the art equipment primarily for solution NMR (Bruker 500, 600, 700, and 800, Varian 400 and 600 MHz spectrometers), and a solid state capacity has been added to the Bruker 800 MHz spectrometer. Recently we were able to update the Bruker 600 and 700 MHz spectrometers to HDneo consoles and install new cryoprobes with superior sensitivity and capability to do direct 13C detect as well as 19F experiments.

 

 

Location and hours of operation

 

Instrument

Hours

Location

Facility Phone Number

700MHz

9 AM – 6 PM

Millis-G10,  2080 Adelbert Road, Cleveland, Ohio 44106

216-368-8833

600MHz

9 AM – 6 PM

KHS-28,     2100 Adelbert Road, Cleveland, Ohio 44106

 

500MHz

9 AM – 6 PM

Millis-G10,  2080 Adelbert Road, Cleveland, Ohio 44106

216-368-8833

Links and Resources

      Safety document & Training section document

  1. NMR Training & Safety document   & TOPSPIN (user -Manual)  (Please read safety document, before you schedule the training section)   
  2. Bruker Beginers Guide manual (describe the basic components of a Bruker spectrometer,their functionality)_ Topspin-3.2
  3. NMR Reference Standard sample form Bruker 5mm Probes

       I-lab (NMRCORE)

  1. Instructions for Creating i-lab account & login (Internal customers)
  2. Instructions to the principal investigator to approve the I-lab membership for His/Her group
  3. Instructions for Creating I-lab account & login (External customers)
  4. Instructions to users to Schedule the NMR instruments and Edit or delete the reservations
  5. Instructions to users to download the FID files (FTP) from NMR instrument computer
  6. Parking-permit (CCMSB_NMR facility)
  7. Download the fugu

      Experiments &Data_Processing

     1.NMRpipe_Data_processing

      Links

  1. North East Ohio High Field NMR Facility
  2. NMR User Fees
  3. CWRU Core Facilities

Contacts

Name Role Phone Email Location
Gregory P. Tochtrop, PhD
Core Director
 
216-368-2351
 
gregory.tochtrop@case.edu
 
Millis 410A
 
Atul Srivastava, PhD
Core Manager
 
216-368-2404
 
atul.srivastava@case.edu
 
224A, Mills Hall, Chemistry Dept.
 

Available Equipment and Resources

► Available NMR Spectrometers (3)
► Decommissioned (3)