Northeast Ohio High Field NMR Facility

Overview of Services

Nuclear Magnetic Resonance (NMR) Spectroscopy is a very versatile technology for the characterization of structure and dynamics of small molecules as well as biological macromolecules in solution (even as part of mixtures and in cells), but also in membrane mimicking environments, in solid powders or microcrystals.  The facility houses state of the art equipment primarily for solution NMR (Bruker 500, 600, 700, and 800, Varian 400 and 600 MHz spectrometers), and a solid state capacity has been added to the Bruker 800 MHz spectrometer. Recently we were able to update the Bruker 600 and 700 MHz spectrometers to HDneo consoles and install new cryoprobes with superior sensitivity and capability to do direct ¹³C detect as well as ¹⁹F experiments.

 

 

Location and hours of operation

 

Instrument	Hours	Location	Facility Phone Number
700MHz	9 AM – 6 PM	Millis-G10,  2080 Adelbert Road, Cleveland, Ohio 44106	216-368-8833
600MHz	9 AM – 6 PM	KHS-28,     2100 Adelbert Road, Cleveland, Ohio 44106
500MHz	9 AM – 6 PM	Millis-G10,  2080 Adelbert Road, Cleveland, Ohio 44106	216-368-8833

Links and Resources

      Safety document & Training section document

1. NMR Training & Safety document   & TOPSPIN (user -Manual)  (Please read safety document, before you schedule the training section)   
2. Bruker Beginers Guide manual (describe the basic components of a Bruker spectrometer,their functionality)_ Topspin-3.2
3. NMR Reference Standard sample form Bruker 5mm Probes
   

       I-lab (NMRCORE)

1. Instructions for Creating i-lab account & login (Internal customers)
2. Instructions to the principal investigator to approve the I-lab membership for His/Her group
3. Instructions for Creating I-lab account & login (External customers)
4. Instructions to users to Schedule the NMR instruments and Edit or delete the reservations
5. Instructions to users to download the FID files (FTP) from NMR instrument computer
6. Parking-permit (CCMSB_NMR facility)
7. Download the fugu

      Experiments &Data_Processing

     1.NMRpipe_Data_processing

      Links

1. North East Ohio High Field NMR Facility
2. NMR User Fees
3. CWRU Core Facilities

Contacts

Name	Role	Phone	Email	Location
Gregory P. Tochtrop, PhD	Core Director	216-368-2351	gregory.tochtrop@case.edu	Millis 410A
Atul Srivastava, PhD	Core Manager	216-368-2404	atul.srivastava@case.edu	224A, Mills Hall, Chemistry Dept.

Available Equipment and Resources

▼ ► Available NMR Spectrometers (3)

Name Price 700 MHz Bruker-BioSpin Avance NEO NMR Spectrometer   600 MHz Varian Inova NMR Spectrometer (Macro600- Schedule/Walkup)   600 MHz Bruker-BioSpin Avance ICE NMR Spectrometer

▼ ► Decommissioned (3)

Name Price 900 MHz Bruker-BioSpin Avance II NMR Spectrometer   800 MHz Bruker-BioSpin Avance I NMR Spectrometer   400 MHz Varian Inova Spectrometer (Chem400- Walkup/No schedule)