Germ-Free Mouse Models Core

                                          

Overview of Services

Research exploring the role of the microbiome, with particular emphasis on the gut microbiome, is growing rapidly, affecting almost every organ in the body and every discipline in biology and medicine. One very important approach to study the functionality of the gut microbiome is the use of Germ-Free (GF) Mice, which are bred in gnotobiotic facilities. The Germ Free Mouse Models Core of the Case Digestive Health Research Institute (DHRI) is housed in the Animal Resource Center (ARC) of the Biomedical Research Building (BRB) and provides a comprehensive and unique set of services for the greater research community. 

 

Services Provided:                                                                                  

  • Gavaging of bacteria or fecal matter
  • Intraperitoneal (IP) drug administration
  • Mouse weighing
  • Germ-free double cage husbandry
  • Organ and tissue collection
  • Assistance in preparing IACUC amendments regarding germ-free animal usage for individual laboratories
  • Germ-free rederivation and subsequent genotyping

 

                                                                                                                                                          

 

Leadership and Support Staff

Fabio Cominelli, MD, PhD

Core Director

216-844-7344

fxc90@case.edu

BRB 524

Alexander Rodriguez-Palacios, DVM, PhD

Core Co-Director

216-368-8545

axr503@case.edu

BRB 525

Tracy Krebs, MBA

Core Administrative Director

216-368-6058

tls23@case.edu

BRB 523

 Dennis Gruszka

iLab Support     Administrator - Interim Core Manager  216-368-1105  drg59@case.edu  BRB 519

Madison Bell

Core Support Specialist

 216-368-0756

mnb68@case.edu

BRB 509A

Taliba Hodge

Core Support Staff

  216-368-0756

 tih9@case.edu

 BRB 509A

       

 

 

 

Location and Hours of Operation

                                                                                                                                                                                                                                          

Monday - Friday       9AM - 5PM

 

2109 Adelbert Road 

BRB 509A

Cleveland, OH 44106

Ph: 216-368-0756


 

 

 

 

 

                                                                                                                                 

Links and Resources

The Case DHRI

                                                          

 

 

Contacts

Name Role Phone Email Location
Tracy Krebs
Core Administrative Director
 
216-368-6058
 
tls23@case.edu
 
BRB 523
 
Madison Bell
Core Support Specialist
 
216-368-0756
 
mnb68@case.edu
 
BRB 509A
 
Dennis Gruszka
iLab Support Administrator - Interim Core Manager
 
216-368-1105
 
drg59@case.edu
 
BRB 519
 

Service list


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Animal Purchase (3)
Cage and Supply Charges (1)
Services (3)

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