Case Western Reserve University’s Core Facilities and Centers provide access to state-of-the-art equipment and instrumentation, service work, technical expertise, and training all designed to support innovation and cutting-edge research

 

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Please contact cwrucores@case.edu for help with general questions related to our Core Facilities and Centers.

iLab Cores at Case Western Reserve University

Core Name Primary Contact Email Phone Number/Ext
Applied Functional Genomics Core

The AFGC provides functional genomics study design and a standardized platform for RNA isolation, Illumina-based bulk, single-cell, and spatial multiomics, plus bioinformatics across diverse clinical sample types.

Mark Cameron mark.cameron@case.edu 216-368-3196
Bioanalyte Core

The Bioanalyte Core offers gene expression, protein quantification, and biomarker function analysis from various species and sample types, including tissue, serum, plasma, mucous fluids, tears, BAL fluid, and CNS.

Tracey L. Bonfield tracey.bonfield@case.edu 216-368-4558
Biomedical Engineering Resources Core

Dominique Durand dominique.durand@case.edu 216-368-3974
CDDRCC Histology

The Histology/Imaging Core provides high-quality, cost-effective and time-efficient histological and imaging analysis of human and animal tissues of digestive inflammatory and metabolic diseases, such as inflammatory bowel disease, hepatitis, metabolic syndromes and obesity.

Theresa Pizarro Theresa.pizarro@case.edu
CFAR Clinical Sciences Core

CFAR Viral Pathogenesis and Persistence

Benjamin Luttge, Ph.D. benjamin.luttge@case.edu (301)643-7969
CVRI Mouse Metabolic Phenotyping Core

The CVRI Mouse Metabolic Phenotyping Core (MMPC) uses the Sable (Sable Systems International) Promethion cage system for single-mouse whole body respirometry, body weight monitoring, and continuous food intake and activity measures.

Armando Vergara-Martel armando.vergara@case.edu
Center for Advanced Research Computing

Center for Medical Mycology

Research at the Center for Medical Mycology (CMM) is devoted to the following main areas: Fungal Susceptibility Testing, and Mycology services; and Microbiome and Cellular Services

Lisa Long lisa.long@case.edu 216-983-3094
Chemical Engineering Instrumentation Core (CHiC)

The Chemical Engineering Instrumentation Core at Case Western Reserve aims to provide top-tier chemical identification and analysis techniques to CWRU and the greater Cleveland communities by providing access to spectroscopy, gravimetry, imaging and more.

Laurie Dudik laurie.dudik@case.edu 216-368-2211
Cryo-Electron Microscopy Core Facility

The facility is set up to study flash-frozen samples by Cryo-EM Single-Particle Analysis (SPA), Cryo-electron Tomography (Cryo-ET) and conventional TEM services including sample processing, ultramicrotomy, film developing, and photographic printing, as well as immunocytochemistry.

Kunpeng Li kunpeng.li@case.edu 7654215516
Cystic Fibrosis Mouse Models Core

The Cystic Fibrosis (CF) Mouse Models Core at Case Western Reserve University (CWRU) produces, characterizes and exports various Cystic Fibrosis Mouse Models for CF research.

Cytometry & Imaging Microscopy Core

The Cytometry and Microscopy Shared Resource provides access to instrumentation to perform cell-based assays and cell sorting.

Cytometry & Imaging Microscopy Core cytocore@gmail.com 216-368-5267
DDRCC Biorepository Core

The Biorepository Core procures, provides and stores DNA, serum, and biopsy and surgical tissues from patients with gastrointestinal and liver diseases as well as normal controls for use in Institutional Research Board-approved research.

Tracy Krebs, MBA tracy.krebs@case.edu 216-368-6058
DDRCC Mouse Models Core

The Mouse Models Core of the Cleveland DDRCC provides members with access to a comprehensive set of services and unique mouse models to support in vivo investigations of digestive diseases involving inflammatory and metabolic processes.

Tracy Krebs, MBA tracy.krebs@case.edu 216-368-6058
Electronics Design Center

The Electronics Design Center (EDC) specializes in electrochemistry and microfabrication, supporting university researchers, educating students, and providing prototyping and R&D services to external organizations.

Rohan Akolkar, PhD rohan.akolkar@case.edu 216-368-4151
Engineering Services Fabrication Center

The Engineering Services Fabrication Center (ESFC) and its machine shop offer the design and fabrication of unique mechanical devices and complete systems to meet a broad range of research requirements.

Engineering Services Fabrication Center esfc@case.edu 216-368-4019
Genomics Core Facility

The Genomics Core provides DNA/RNA sequencing using Illumina NovaSeq X Plus, NextSeq 550, and MiSeq, along with quality assessment, library prep, and BeadArray methylation and genotyping analysis.

Simone Edelheit simone-edelheit@case.edu 216-368-1887
Germ-Free Mouse Models Core

The Germ-Free Mouse Models Core of the Case Western Reserve University Digestive Health Research Institute (DHRI) provides a comprehensive and unique set of services to explore the gut microbiome.

Tracy Krebs tracy.krebs@case.edu 216-368-6058
Hematopoietic Biorepository and Cellular Therapy Core

The HBCT Shared Resource provides services for procuring, processing, storing, analyzing, and distributing cells from human blood, bone marrow, and umbilical cords.

Jane Reese jane.reese@case.edu 216.368.1007
Imaging Research Core

The Imaging Research Core provides a comprehensive suite of preclinical and clinical imaging instrumentation and techniques developed in-house by our leading imaging scientists. The core offers the expertise, infrastructure and environment that can help turn your research into a reality.

Chris Flask christopher.flask@case.edu 216-844-4963
Light Microscopy Imaging Core

The Light Microscopy Imaging Core provides shared access to transmitted light, live-cell, confocal, multi-photon, deconvolution, super resolution, and slide scanning (brightfield and fluorescence) imaging services for the research community.

Michael Jenkins, PhD michael.jenkins@case.edu 216-368-1488
MORE Center

The MORE Center facilities enable a wide range of materials deposition, micro and nanoscale lithographic fabrication, structural and materials-based characterization techniques for a variety of materials and devices. This includes facilities for emerging optoelectronic technologies.

Andrew Lininger andrew.lininger@case.edu 216-368-4007
Microfabrication Laboratory (MFL)

Nichole Hoven nichole.hoven@case.edu 216.368.0264
Mitochondrial Core

The Mitochondrial Research Core provides services to examine the composition and function of mitochondrial protein complexes. This includes functional assays that measure electron transport chain (ETC) activity in cells and in isolated complexes.

Jason Mears jason.mears@case.edu 216-368-3348
Mouse Behavioral Phenotyping Core

The Mouse Behavioral Phenotyping Core conducts comprehensive behavioral testing in mice, assessing motor, sensory, cognitive, emotional, and social functions tailored to investigators’ research needs.

Ian Adams ian.adams@case.edu 216-368-6179
Neurodegenerative Research Core

The Neurodegenerative Research Core provides access to human tissue and bodily fluids from patients suspected of neurodegenerative diseases. It offers routine histologic and special stains and immunohistochemical stains specific for neurodegenerative diseases.

Keisi Kotobelli keisi.kotobelli@case.edu 216-368-0587
Northeast Ohio High Field NMR Facility

NMR Spectroscopy is a versatile technique to study the structure and dynamics of small molecules and biomacromolecules in solution, mixtures, cells, membranes, solids, or microcrystals.

Gregory P. Tochtrop, PhD gregory.tochtrop@case.edu 216-368-2351
Proteomics and Small Molecule Mass Spectrometry Core

The Proteomics and Small Molecule Mass Spectrometry Core services include: Structural Proteomics (Radiolytic footprinting and GEE labeling), Quantitative Proteomics (Global Phospho-Proteomics), Small Molecule Mass Spectrometry (Single Reaction Monitoring)

Daniela Schlatzer daniela.schlatzer@case.edu 216-368-4014
RNA Profiling Core

The Advanced RNA Profiling Core performs cutting edge, sequencing-based, transcriptomic profiling techniques, (ribosome profiling, CLIP, 3’end transcript mapping, etc.) as a full service or through a la carte services.

Frank A. Tedeschi frank.tedeschi@case.edu 368-6711
SDLE Research Center

The SDLE Research Center focuses on materials data science, studying durability and degradation of long-lived materials through advanced characterization, accelerated aging, and high-performance computing using the CRADLE platform.

Small Molecule Drug Development Core

The Small Molecule Drug Development Shared Resource (SR) optimizes robust assays in 384-well format and to screen large chemical libraries to identify new small molecules for innovative cancer therapeutics.

Soft Matter Characterization Laboratory

Soft Matter Characterization Instruments include thermal analysis, molecular weight characterization, microscopy and X-ray scattering.

Lei Zhu lei.zhu2@case.edu 216-368-5861
Surgical Training and Research Core

The Surgical Training and Research (STAR) Core provides surgical resources for education and research.

Steve Schomisch, PhD steve.schomisch@case.edu 216-368-6611
Swagelok Center for Surface Analysis of Materials

The Swagelok Center for Surface Analysis of Materials provides specialized analytical equipment with expert staff support to solve materials characterization challenges encountered in education, research and industry.

Jeffrey Pigott jeffrey.pigott@case.edu 216-368-6012
Tissue Resources Core

The Tissue Resources SR supports Cancer Center researchers by providing high-quality human tissues and priority histology, IHC, tissue microarray, and in situ hybridization services for human and animal samples.

Adam Kresak, MS adam.kresak@case.edu 216-844-5389
Translational Shared Resource

Translational Research Services and Technologies offers sample handling, processing, lab analysis, preclinical drug testing, PK assays, and clinical trial study design support, along with translational and pharmacology lab resources.

Erin Hohler erin.hohler@case.edu 216-286-3889
bio[box]

bio[box] is a shared instrumentation facility with basic and advanced molecular biology instruments and microscopes. It is open to trainees, staff and faculty to use independently after sufficient training.

Radhika Atit radhika.atit@case.edu
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